Aging is an inevitable part of life, but advancements in aesthetic medicine are revolutionizing the way we address it. From plastic surgery to dermal fillers and beyond, the need for effective, long-lasting anti-aging solutions has driven continuous innovation. Today, there is a better understanding that true skin rejuvenation isn’t just about adding volume - it’s about restoring the skin’s natural ability to heal and regenerate.

For years, traditional dermal fillers have been the go-to for restoring facial volume and smoothing wrinkles. These fillers, often made from hyaluronic acid (HA) - a naturally occurring substance in the skin - work by physically plumping targeted areas, providing instant, yet temporary, results. 

As patient expectations evolve, there’s been a shift towards treatments that offer more natural, long-lasting results - leading to the growing popularity of biostimulator injections. 

What are Biostimulators?

Biostimulators are advanced injectable treatments designed to go beyond simply filling wrinkles or adding volume. Unlike conventional fillers that simply "fill," biostimulatory injectables take a regenerative approach. They work beneath the skin’s surface to stimulate the body’s own collagen production through a biological process known as neocollagenesis - the formation of new collagen.

Collagen is a vital protein responsible for skin’s firmness, elasticity, and overall structure. Unfortunately, as we age, natural collagen production declines, leading to wrinkles, sagging, and volume loss. Biostimulators help reverse this process by encouraging the face to produce fresh collagen, thereby rebuilding the skin from within. This results in improvements that are not only more natural-looking but also longer-lasting.

Another key benefit of biostimulatory fillers is their gradual, subtle effect. Rather than seeing an immediate, dramatic change (which can sometimes appear unnatural), results develop progressively over several weeks to months as collagen production increases. This makes biostimulators particularly appealing to individuals seeking a more understated, authentic enhancement - without the risk of an "overfilled" or artificial appearance.

Who Can Benefit from It?

This biostimulatory filler is ideal for individuals who are looking to:

- Achieve long-lasting skin rejuvenation with gradual, natural improvements

- Restore volume in key areas of the face including cheeks, jawline, and chin

- Experience non-surgical lifting effect for a refreshed, youthful look

- Enhance skin elasticity and texture through collagen stimulation

- Choose a scientifically backed, safe, superior quality, and trusted solution

With the increasing popularity of biostimulatory injectables, aesthetic medicine has reached a new frontier - offering treatments that not only fill but heal and rejuvenate from within.

This is where Genefill DX comes into play - a biostimulatory filler that takes these benefits to the next level.

Genefill DX: A Game Changer in Anti-Aging Treatments

Genefill DX is the perfect example of innovation and advancement in aesthetic medicine. It is changing the game for biostimulatory fillers and delivering results that not only provide volume restoration but also stimulate natural collagen production for long-lasting rejuvenation.

Similarly to our other products, Genefill DX is at the forefront of innovation in the world of dermal fillers. It offers a next-generation collagen stimulant that works deep within. This results in long-term rejuvenation, improved elasticity, and a natural feel that enhances your beauty over time.

Why Genefill DX is a Game Changer:

Hybrid Filler Technology

It’s a unique, hybrid product that contains Hyaluronic Acid and Dextranomer microparticles. This makes for an increased contouring and filling effect for the mid to deep dermis. 

Deep Tissue Stimulation

Unlike traditional fillers that simply add volume, our product penetrates the deeper layers of the dermis to boost collagen and elastin production naturally.

Sustained, Natural-Looking Results

With its cutting-edge hybrid formulation, Genefill DX ensures long-lasting improvement in skin texture and firmness, with results that can last up to two years.

Minimally Invasive, Maximum Effectiveness

It offers a quick application with minimal downtime, making it the best anti-aging treatment for individuals seeking non-surgical dermal rejuvenation.

Biocompatible & Clinically Proven

Safety is, of course, the most important aspect to consider with dermal fillers. Genefill DX is developed with biocompatible formulation that ensures optimal results with minimal risks.

The Science Behind Biostimulatory Injectables

Conventional dermal fillers, that are predominantly composed of hyaluronic acid, provide instant volume but require a lot of upkeep and frequent maintenance. On the other hand, biostimulatory injectables take enhancement much further by stimulating collagen renewal from within. 

With Genefill DX, it interacts with the skin’s extracellular matrix upon injection, promoting collagen-stimulating dermal filler properties. This process leads to gradual yet noticeable improvements in your overall appearance, making it the smart, preferred option for those seeking long-term solutions for skin aging.

The Advanced HA + DX Formulation: A Synergistic Approach to Skin Rejuvenation

Genefill DX is powered by an innovative HA + DX formulation, uniquely designed to deliver both immediate and long-term skin enhancement. 

Hyaluronic Acid (HA), a gold-standard ingredient in dermal fillers, provides instant hydration and volumization, plumping the skin for a youthful, refreshed appearance. Meanwhile, Dextranomer (DX) plays a pivotal role in promoting neocollagenesis and providing a lifting effect, ensuring that the skin remains firm and resilient over time.

Synergistic Effects for Superior Results

The combination of HA’s hydrating and volumizing properties with Dextranomer’s regenerative capabilities ensures a comprehensive anti-aging effect. This hybrid formulation enables increased contouring and filling for the mid to deep dermis, offering superior support to facial structures while encouraging extracellular matrix remodeling for long-term benefits.

The Science Behind HA + DX

Dextranomer microspheres, composed of dextran molecules with a positive surface charge, are hydrophilic and biodegradable. These properties enable enhanced cell signaling and fibroblast activation, ensuring rapid tissue repair and regeneration. Studies have demonstrated that HA + DX stimulates significantly higher cell proliferation, accelerating healing and improving overall skin quality.

Additionally, Genefill DX significantly boosts the production of Collagen I, III, IV, and Elastin, surpassing traditional fillers in regenerative performance. Collagen III production is particularly superior with HA + DX, reinforcing skin resilience and elasticity, making it an optimal choice for long-lasting rejuvenation.

Anti-Inflammatory and Regenerative Properties

Genefill DX not only enhances collagen production but also modulates inflammatory responses to support optimal healing. It significantly increases anti-inflammatory cytokines such as TGF-β1, IL-10, and IL-6, while reducing pro-inflammatory cytokines like TNFα at 72 hours, ensuring balanced inflammation control. Unlike some fillers, HA + DX maintains stable IL-1β levels, confirming no unintended pro-inflammatory activation.

These combined properties position Genefill DX as a scientifically advanced, high-performance dermal filler that actively supports skin regeneration and tissue remodeling, ensuring comprehensive and long-lasting aesthetic benefits.

Genefill DX vs. Traditional Fillers

Genefill DX is the smart choice for your dermal filler needs - and to help you make the right, informed decision, here is a breakdown of how it holds up against traditional fillers:

Leading the Future of Anti-Aging Treatments

As the beauty industry is shifting towards treatments that prioritize safety, natural-looking, and long-term skin health, we’re setting the standards in advanced aesthetics. Anti-aging solutions don’t need to be limited to short-lived fixes anymore - patients are looking for treatments that work with their body’s natural processes for the most synergised results. 

By investing in biostimulator injections, patients receive a treatment that improves skin texture, elasticity, and firmness over time, without the need for constant touch-ups. The power of neocollagenesis ensures a youthful and healthy complexion for years to come.

Elevate Your Aesthetic Practice with Biostimulators

For aesthetic practitioners, incorporating biostimulatory injectables into your clinic means offering the most advanced biostimulatory injectables available today. With its unique formulation and ability to restore, rejuvenate, and regenerate, Genefill DX sets a new benchmark in non-surgical facial enhancement.

At Genefill, we are pioneers in the field of aesthetic medicine, delivering solutions that are scientifically advanced and trusted by professionals worldwide. Compared to other biostimulatory fillers now emerging in the market that use PLLA and CaHa that are synthetic biostimulators, Genefill DX uses Dextranomer, which is natural and provides much better results. 

Discover the future of biostimulator and hybrid filler technology with Genefill DX - where science meets artistry for timeless beauty.

Contact us for more information and get everything you need to take a step towards the future of aesthetic medicine.